Antech Diagnostics
17672-A Cowan Avenue Irvine CA 92614 Phone: 800-745-4725
Hemopet/Hemolife Client # 20073
11330 Markon Dr Chart #
Garden Grove, CA 92841
Tel: 714-891-2022
Fax: 714-891-2123
Accession No. Doctor Owner Pet Name Received
IRBD44962641 HEIJDEN DELAPLANE
Andrea
Species Breed Sex Pet Age Reported
Canine Great Dane Female 4Yrs 07/22/2008 06:49 AM
61. 5 kg (135. 3 lbs)
Test Requested Results Reference Range Units
T3 (RIA)
T3 (RIA) 105 45-150 ng/dL
T4
T4 2.01 1.0-4.0 mg/dL
Free T3
Free T3 4.9 1.7-5.3 pg/mL
Free T4 (RIA)
Free T4 (RIA) 0.82 0.45-2.06 ng/dL
T3 Autoantibodies
T3 Autoantibodies 3.6 (HIGH) Less Than 2.0 AUTOIMMUNE
Results have been rechecked and verified. THYROIDITIS !
T4 Autoantibodies
T4 Autoantibodies 4.5 (HIGH) Less Than 2.0 AUTOIMMUNE
Results have been rechecked and verified. THYROIDITIS !
Thyroglobulin Autoantibodies
Thyroglobulin Autoantibody 52
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< 10% = Negative; 10%-25% = Equivocal; > 25% = Positive
Elevated TGAA levels confirm autoimmune thyroiditis. False positive results can occur if the dog has been vaccinated for rabies within 30 to 40 days. Thyroid hormone supplementation can decrease TGAA levels.
TGAA is performed at Hemolife using the preferred Non-Specific Binding (NSB) Method.
Dear Paul: Wow ! Autoimmune thyroiditis IS present here, and has progressed to hypothyroidism
with the current clinical signs. As TgAA is positive, this explains her clinical and behavioral issues.
This is a great case ! T3AA and T4AA , as expected , are also positive. Jean
Large Breed T4 1.5-3 mg/dL FT4 0.7-1.5 ng/dL T4AA < 2.0
Optimal Levels T3 50-150 ng/dL FT3 1.7-5.3 pg/mL T3AA < 2.0
X These results confirm autoimmune thyroiditis, the heritable form of canine thyroid disease. Elevated levels of T3AA and/or T4AA cause spurious elevations in T3/FT3 and/or T4/FT4 because these circulating autoantibodies interfere with laboratory tests of thyroid analytes. The lymphocytic infiltration and gradual destruction of thyroid tissue progresses to end-stage hypothyroidism, as determined by the clinical signs and low T4 and/or FT4 values referable to thyroid disease.
Accession No. Doctor Owner Pet Name Received
IRBD44962641 HEIJDEN DELAPLANE
Test Requested Results Reference Range Units
Recommend 6-12 weeks of Soloxine ® or equivalent product at 0.1 mg per 15 lbs twice daily (e.g. 0 . 7 - 0. 8 mg BID). Retest thyroid profile drawing the sample 4-6 hours post-pill (to reassess levels which should be upper 1/3 to 25% above the resting ranges, and see if thyroid AA levels are waning). Dose at optimum weight.
X Elevated levels of thyroglobulin autoantibodies are diagnostic of lymphocytic thyroiditis.
X As autoimmune thyroiditis is the heritable form of canine thyroid disease, we do NOT recommend using this dog for breeding.
To ensure absorption, thyroxine is best given by mouth, at least 1 hour before or 3 hours after a meal.
By Fax to clinic at 011-31-10-492-5145 , and e-mail to client at adelaplane@wanadoo.nl